comicbookguy
Super Freak
The sought after stuff with lowest edition sizes will generally hold value and continue to rise in the long run.
This is generally the older stuff. Unless the company decides to re-release the same item, you don't have to worry too much.
You can make profit from anything you buy, just need to be able to buy it for the right price and sell it at the right time. As mentioned before.
How about comics, episode 1 toys, and spawn figures?