Typically the best day to buy stuff is the last day, because the exhibitors will put most of their stuff on sale. Typically because they don't want to have to pack it up and lug it back to their shop/home or they are just trying to make money to cover the costs of the convention.
That being said, if you wait until the end some of the convention exclusives may be taken, so you'll probably want to check their website or the exhibiting companies websites to see what exclusives they will be having there.
This convention will be nowhere near the size of SDCC, so don't expect to see all the statues and toys that you see in the pictures from SDCC. There'll most likely be toy shops there selling statues and stuff, and most will still be in the box with very few actually being displayed. These conventions are typically a good place to meet and actually talk to artists (unlike SDCC where they are pretty busy being surrounded by fans wanting sketches and autographs) and typically I see better quality sketches coming out of the smaller conventions (smaller meaning anything smaller than SDCC).
Check the schedule online for panels, perhaps they will be discussing something that you want to hear about. There will be some celebrities there so you may want to check for signing schedules/panels to find out when and where those events are taking place.
Once you have your list of exclusives, artists, celebrities, and panels that you want to purchase/see/attend then start piecing together a schedule that will fit all of those as best as possible. If you are going to be attending the preview night (if they offer one) then that is usually the best time to quickly check out the exclusives and get a general idea where everything is. From there, just try to follow your schedule and if you have downtime walk around and see what is happening and take pics, possibly talk more with some of your favorite artists.
Typically the days start getting gradually worse. Usually Saturdays are the busiest for conventions. Sundays seem to be more of a family day and usually have more kid friendly programming.
Not sure what else to say. Just make it your own and don't kill yourself trying to get to everything. It's not always possible to get to it all.
Good luck and enjoy!!