I only have 5 1/6 figures -- Bauer, BR Joker, DX Joker, Two-Face and Indiana Jones. I guess that leaves TDK as the primary line, but I'm not sure I'd classify three figures as a "line".
But, if you include smaller figures and general collectibles ...
Star Trek
Indiana Jones
Jurassic Park
Football (Dallas Cowboys)
Baseball (Houston Astros)
24 (they haven't released a ton, though)
DC -- Superman/ Batman/ TDK/ JLA/ Smallville
HK Sidearms ... a small but growing collection
I have a few other piecemeal collectibles (Star Wars 3.75, a few MOTUC, a couple of God of War figures, and a Terminator or two).
SnakeDoc