I doubt it, but Crytek have said in the past that the CryEngine used for C2 is a lot more scalable than the original engine for Crysis. You might be able to get away with the same settings, but I worry my Intel q6600 and Radeon 4870 will get me far.
In the end I think it'll depend on how much of a difference rendering a urban city is to rendering a full scale jungle rich with foliage. The difference in setting might dictate performance. Who knows.
I'm using a Intel Core i7 930 @2.80GHz, but I dont have a very gd GPU. It's a nvidia GT330, one of those repackaged GPU for oem models.
I'm able to run Crysis with most settings on very high and some adjusted to medium or high and still get an average of 20 to 30fps, which is still very playable for me. Downloading the realistic foliage mod did help to make the game look a lot prettier without totally killing my GPU.
Really hope, I'll be able to do the same for Crysis 2.........worst come to worst I may upgrade the GPU once the warranty runs out.