Well I can't speak to the quality of Spectre, and I understand that Biel is more recognizable than whats-her-face as an actress, but I'm not sure we have much to go on in terms of estimating HT's success selling "sexy" toys. It is obviously a cash cow for Sideshow, but that success may not translate to HT figures.
Beyond Spectre, I've seen the Machiko Predator available for sub-$100 on several occasions, Sheva seems to be the least popular of the Res. Evil figures, and the Silken Floss wasn't really released in large enough numbers for us to gauge that figure's popularity (not sure what other "sexy" toys HT has released recently). I suppose Black Widow may give us a better impression, but both that character and actress are about 100X more recognizable than Whistler's daughter/Biel, IMO. I'm sure the figure will look very good, but if they hope to move toys based on the "sexyness" of the figure alone, along with the fact that she comes with a cross-bow (I guess), then it does not seem like a big hit in the making to me.
Also, the Blade figure kicks ass. No dispute. If you don't get that toy, then that's your bad.