Well visually, I think myself and many others feel that its a very captivating experience. Whether practical or digital VFX, I enjoyed it all. From the vast landscapes of LV-223 and what is presumably Earth (at the beginning) from the interior of the Prometheus. I was also very pleased with the design and final concept of the Engineer, not only physically intimidating but intellectually as well. Which we learned as we dove further into the story. I will admit though I would have liked to see some more destruction caused by the awakened Engineer at the end.
I think in regards to the characters Michael Fassbender's portrayal of David was spot on, I really think he made the final version of the script work well in his favor. Regardless of its flaws through the revisions. I especially liked the relationship or lack there of between David and Holloway. I especially enjoyed the scene where David places the black liquid in Holloway's glass. I felt it was inevitable that something was coming to Holloway considering his attitude towards David. The comic relief provided by Janek, Fifield, and Milburn were enough for me as the story progressed, and was well balanced throughout the film. I guess the only character that bugs me is Vickers solely because I am still not convinced she was human. Although I felt it still wasn't confirmed with any concrete examples.
Now the story itself was nothing I had expected upon my first viewing as I refused to read anything about it. I enjoyed it for what it offered, minus the plot holes that have been listed many times before by fellow members. I found some scenes rushed as the action really started to pick-up after the films' climax. Which could sometimes be typical in any film. As I had mentioned before in this thread I would have liked to see our little baby Deacon explore its territory some more. Which I recently found out in the concept art from the Art Of Prometheus there are some drawings of the Deacon exploring the terrain. I am really looking forward to a sequel, hopefully one that begins where this left off, and possibly a visit to the Engineer's home planet.
Overall it was a great movie and I'm looking forward to the sequel sometime soon . . .