Didn't see this posted yet but a good interview on Newsarama from Glen Mazzara.
On more than one occasion, it was brought to Mazzara’s attention that some viewers thought Lori Grimes was, as one reporter puts it, "irritating." Mazzara refuted that statement bluntly, arguing his intentions for the character in his tenure on the show.
“I think Laurie is a compelling and interesting character,” explains Mazzara. “She’s realistic in a lot of ways, and certainly a character people are talking about. In season three, we really begin to look at Rick and Lori’s relationship and what it means that she put Rick and Shane on a collision course to kill each other.”