It's a very different experience from Berserk, but shares some similarities in the sense that both Guts and Musashi both want to find meaning in their lives, but Vagabond takes it to it's fullest extent. It's essentially all about self growth and finding purpose. The whole Manga is based on the novel "Musashi" written by Eiji Yoshikawa who wrote it about his entire life. While the Manga takes liberties with his life and his duels, it's made very interesting with all the characters being very fleshed out. No wasted chapters.
The real Musashi was a God of combat. Had 60 duels, and never lost.