There are a few tips I can give you that I learned from a Gaspari rep. He said, first off... don't take it after a breakfast or other meal that includes a protein shake. Or else, you will probably get an upset stomach or a very soon restroom trip.
Make sure that your meal before taking this is a solid meal of real food.
Secondly, be sure to allow 45 mins to an hour to elapse before you hit the gym. As it sometimes will make you burp during your workout and overall just make you uncomfortable.
After I started following those basic rules, I no longer had any problems. At first I waited like 25 mins and then went, and as I was on the treadmill all I did was burp... and sometimes I would have to stop running to go and hit the toilet. It was never excessive, but annoying.
But you will get the hang of it, and you will never go a workout session without a fantastic....AMAZING pump.