I can't say the US caused the problem in the Middle East, although they have not helped it. The Middle East would have plenty of issues if the US had zero involvement. You have a groups of people under the same basic umbrella religion that hate each other. You have the issue with Isereal and all the other Middle East continues, you have Pakastan and India (at least you use to).
If it had been left unchecked and left on their own I wouldn't be shocked if that region was uninhabitable. Pakistan and India would have nuked each other, Isreal would have nuked anyone who tried to attack them.
If it had been left unchecked and left on their own I wouldn't be shocked if that region was uninhabitable. Pakistan and India would have nuked each other, Isreal would have nuked anyone who tried to attack them.