Tyrion's nose would have just been tough to do no matter what method they removed it with (cig, make up, both, etc). I think they made a good compromise with just the big scar(s) running diagonally through his face. I always felt it was a bit much in the book anyway. Tyrion life is difficult enough as it is
I wonder how long it will take them to give Jamie a prosthetic hand. I can't imagine them just CGIing a stump for him for very long.
If they follow the book then he gets a gold hand once he gets back to King's Landing