Maybe not. With Nolan helming at least the production of Superman it sounds like he is giving him the real world treatment as much as possible, using the origins as an anchor. I have a feeling they'll get a director who will try to continue forward with the status quo and if not successful reboot in a couple of years. They'll want to keep the Batman momentum flowing until it craps like Batman and Robin did.
The most logical would be Black Mask especially at his beginnings where he actually wore a black mask. Black Mask hates Bruce Wayne and it adds to the duality of the character based on his origins, I've been spouting that since TDK. As for the Penguin, DC has a record of taking what is successful in media and translating it to their comics instead of vice versa. When the Burton Batman was successful, he went all black for a time period, Penguin even followed suit after Returns for a time period but in reality Penguin is a nickname a childhood taunt, of Copperpot not an indication of what he really looks like. The Penguin is realistic especially in the books as of recent.
Personally I think they are holding out to block them one tentpole at a time, they aren't in the Marvel situation where multiple companies own rights and so films get butted up against another, Green Lantern has 2011, Batman has 2012 and I guarantee Superman has 2013 just in time to keep the rights. GL 2 will probably follow right after in 2014, with the Flash following etc. I don't think DC/WB is in a hurry to flood the market especially since the marketing is so extensive. Once everything starts running and multiple heroes start going I can see a beginning of summer release and a end of summer to bookend the season but I think they'll tred lightly for a bit.
That is only because Sony owns Spidey, rumors are the Fox wants the FF reboot in 2012 and let's not forget Wolverine 2 and First Class on the docket. If you look at Marvel Studios they are being very strategic in putting out the films to not try and oversaturate amongst their releases but when you add in three other studios with rights, you can avoid so many hitting a short period of time. Overall it hurts the films because fans are pulled in so many different directions and it hurts the long term values.
That was kind of a given, even after TDK Nolan said No Joker in the next one because of Heath, He has been on record before about it, he is just reiterating it. The fanboys want another Joker, he doesn't and am glad he won't although if they reboot it'll be recasted.