I reckon Krauser could of taken Saddler down with ease if he wasnt being submissive to Saddler because Wesker wanted him to stick with him until the time was right. However we are not sure if Krausers mutation was down to the T-veronica virus or if he had taken Las Plagas. It was never explained. So maybe saddler could of used his staff to tame him. But his arm did look like a Las Plagas apendage but then in Darkside its his arm thats hit by the King... whatever it was which had the T-Veronica Virus
Darkside Chronicles is great. He was a great good guy as well as a great bad guy. And everybody loves a great " good guy becomes bad, but redeems himself just before death" kind of scene. Especially since him and Leon were brothers in arms kinda thing.