If I had to pick the single or maybe the two most groundbreaking, influential, and impactful films on the US film industry film in the last 27 years (1990-2017), it would be Toy Story (1995)and Toy Story 2 (1999).
Sounds like a joke, but TS was the first full length CGI film, and it single handedly killed traditional animation, and 20 years later, the box office is dominated by CGI animated films from all major studios.
Eh, domestically none of the TS movies outgrossed The Lion King, and adjusted for inflation hand drawn titles like Snow White, 101 Dalmations, Fantasia, Lion King (again), The Jungle Book, and Sleeping Beauty all destroy the highest CG contender (Shrek 2.) All Pixar did was offer a different technique in how pictures are animated.
And if you're simply judging a film's influence based on technique instead of content then AOTC has impacted how countless more movies are filmed than any achievement from Pixar. Content-wise I'd still say that Pulp Fiction, Braveheart, and Saving Private Ryan have been the most influential over the last quarter century.